Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs

Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs

title book:Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs by Li Di edit:1 2015: Year Language English number pages :616 (Print version - electronic version) 1118788354, 9781118788356 Publisher:Wiley type: pdf size:6mb   Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery.• Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects• Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess...